R/minc_vertex_statistics.R
vertexLmerEstimateDF.Rd
There is much uncertainty in how to compute p-values for mixed-effects statistics, related to the correct calculation of the degrees of freedom of the model (see here http://glmm.wikidot.com/faq#df). mincLmer by default does not return the degrees of freedom as part of its model, instead requiring an explicit call to a separate function (such as this one). The implementation here is the Satterthwaite approximation. This approximation is computed from the data, to avoid the significant run-time requirement of computing it separate for every vertex, here it is only computed on a small number of vertices within the mask and the median DF returned for every variable.
vertexLmerEstimateDF(model)
model | the output of mincLmer |
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the same mincLmer model, now with degrees of freedom set
# NOT RUN { vs <- mincLmer(filenames ~ age + sex + (age|id), data=gf, mask="mask.mnc") vs <- mincLmerEstimateDF(vs) qvals <- mincFDR(vs, mask=attr(vs, "mask")) qvals # }